Gene

eppk1

ID

ZDB-GENE-030416-1

Name

epiplakin 1

Symbol

eppk1 Nomenclature History

Previous Names

cb159 (1)
wu:fb54f07

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have keratin filament binding activity and structural molecule activity. Predicted to be involved in intermediate filament bundle assembly and wound healing. Predicted to colocalize with keratin filament. Is expressed in several structures, including EVL; cardiovascular system; epidermis; periderm; and ventral mesenchyme. Orthologous to human EPPK1 (epiplakin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb159 (23 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eppk1 Human Ortholog

No data available

Associated With eppk1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR043197	Plakin
Homologous_superfamily	IPR035915	Plakin repeat superfamily
Repeat	IPR001101	Plectin repeat

Domain Details Per Protein

Protein	Length	Plakin	Plakin repeat superfamily	Plectin repeat
UniProtKB:I3ISA6 InterPro	5476

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	eppk1-201 (1) Ensembl	Ensembl		19,233 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations