Gene

tiam2a

ID
ZDB-GENE-030219-98
Name
TIAM Rac1 associated GEF 2a
Symbol
tiam2a Nomenclature History
Previous Names
  • id:ibd5033
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have Rac guanyl-nucleotide exchange factor activity. Predicted to be involved in activation of GTPase activity; positive regulation of axonogenesis; and small GTPase mediated signal transduction. Predicted to localize to membrane and synapse. Is expressed in somite and tail bud. Orthologous to human TIAM2 (TIAM Rac1 associated GEF 2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from Kudoh et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tiam2a Human Ortholog
No data available
Associated With tiam2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001478 PDZ domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR003116 Raf-like Ras-binding
Domain IPR040655 TIAM1, CC-Ex domain
Family IPR043537 Tiam1/Tiam2/Protein still life
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily Guanine-nucleotide dissociation stimulator, CDC24, conserved site PDZ domain PDZ superfamily PH-like domain superfamily Pleckstrin homology domain Raf-like Ras-binding TIAM1, CC-Ex domain Tiam1/Tiam2/Protein still life
UniProtKB:A0A2R8Q2X5 1611
UniProtKB:A0A286YAC4 1652
UniProtKB:X1WDQ6 186
UniProtKB:A0A286Y9S9 1671
UniProtKB:A0A2R8QJ89 1541
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations