Gene
mtss1la
- ID
- ZDB-GENE-030219-89
- Name
- MTSS I-BAR domain containing 2a
- Symbol
- mtss1la Nomenclature History
- Previous Names
-
- mtss1l
- id:ibd5126
- si:ch211-15i6.4 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable actin binding activity and phospholipid binding activity. Predicted to be involved in cell projection assembly and membrane organization. Predicted to act upstream of or within plasma membrane organization and ruffle assembly. Predicted to be active in actin cytoskeleton and cytoplasmic side of plasma membrane. Is expressed in brain and neural tube. Orthologous to human MTSS2 (MTSS I-BAR domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Kudoh et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| intellectual developmental disorder with ocular anomalies and distinctive facial features | Alliance | Intellectual developmental disorder with ocular anomalies and distinctive facial features | 620086 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | I-BAR domain containing protein MTSS1/MTSS2 | IMD/I-BAR domain | WH2 domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BHP3
|
808 | ||||
|
UniProtKB:A0A8M2BH72
|
758 | ||||
|
UniProtKB:A0A8M3AJH9
|
805 | ||||
|
UniProtKB:Q1LVN6
|
755 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mtss1la-201
(1)
|
Ensembl | 2,283 nt | ||
| mRNA |
mtss1la-202
(1)
|
Ensembl | 2,386 nt | ||
| mRNA |
mtss1la-203
(1)
|
Ensembl | 1,211 nt |
Interactions and Pathways
No data available
Plasmids
No data available