Gene

dph2

ID
ZDB-GENE-030219-100
Name
diphthamide biosynthesis 2
Symbol
dph2 Nomenclature History
Previous Names
  • id:ibd5058
  • zgc:162269 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have transferase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Is expressed in brain; immature eye; somite; and tail bud. Orthologous to human DPH2 (diphthamide biosynthesis 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Kudoh et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dph2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
diphthamide deficiency syndrome 2 Alliance Developmental delay with short stature, dysmorphic facial features, and sparse hair 2 620062
Associated With dph2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010014 Diphthamide synthesis DHP2
Family IPR016435 Diphthamide synthesis DPH1/DPH2
Homologous_superfamily IPR042263 Diphthamide synthesis DPH1/DPH2, domain 1
Homologous_superfamily IPR042265 Diphthamide synthesis DPH1/DPH2, domain 3
Domain Details Per Protein
Protein Length Diphthamide synthesis DHP2 Diphthamide synthesis DPH1/DPH2 Diphthamide synthesis DPH1/DPH2, domain 1 Diphthamide synthesis DPH1/DPH2, domain 3
UniProtKB:A4QN59 498
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations