ZFIN is now using GRCz12tu for Genomic Data
Gene
myh9b
- ID
- ZDB-GENE-030131-998
- Name
- myosin, heavy chain 9b, non-muscle
- Symbol
- myh9b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable actin filament binding activity and microfilament motor activity. Acts upstream of or within several processes, including actin filament bundle distribution; cardiac ventricle development; and midbrain-hindbrain boundary morphogenesis. Predicted to be located in cell cortex; cortical granule; and cytoskeleton. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in several structures, including brain; ectoderm; epidermis; eye; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including auditory system disease (multiple); autosomal dominant Alport syndrome; blood platelet disease (multiple); end stage renal disease; and orofacial cleft. Orthologous to human MYH9 (myosin heavy chain 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 17 | Alliance | Deafness, autosomal dominant 17 | 603622 |
| MYH-9 related disease | Alliance | Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss | 155100 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M2BB06 | InterPro | 1691 |
| UniProtKB:A0A8M1QUS6 | InterPro | 1698 |
| UniProtKB:A0AC58J075 | InterPro | 1960 |
| UniProtKB:A0AC58J082 | InterPro | 1960 |
| UniProtKB:A0AC58J089 | InterPro | 1378 |
| UniProtKB:A0AC58J090 | InterPro | 1953 |
| UniProtKB:A0AC58J093 | InterPro | 1342 |
| UniProtKB:A0AC58J095 | InterPro | 1378 |
| UniProtKB:A0AC58J099 | InterPro | 1953 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers