Gene

tbc1d4

ID
ZDB-GENE-030131-9881
Name
TBC1 domain family, member 4
Symbol
tbc1d4 Nomenclature History
Previous Names
  • cb53 (1)
  • sb:cb53
  • si:ch211-222g23.4
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Is expressed in myotome; pancreatic bud; pronephric duct; and segmental plate. Human ortholog(s) of this gene implicated in acanthosis nigricans. Orthologous to human TBC1D4 (TBC1 domain family member 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tbc1d4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Diabetes mellitus, noninsulin-dependent, 5} 616087
Associated With tbc1d4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000195 Rab-GTPase-TBC domain
Domain IPR006020 PTB/PI domain
Domain IPR021785 Domain of unknown function DUF3350
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035969 Rab-GTPase-TBC domain superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF3350 PH-like domain superfamily PTB/PI domain Rab-GTPase-TBC domain Rab-GTPase-TBC domain superfamily
UniProtKB:F1QE75 1230
UniProtKB:A0A2R8QCT2 1026
UniProtKB:A0A2R8RZV3 207
UniProtKB:A0A0R4ICD0 1061
UniProtKB:E9QC96 202
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations