Gene

kat5b

ID

ZDB-GENE-030131-985

Name

K(lysine) acetyltransferase 5b

Symbol

kat5b Nomenclature History

Previous Names

htatip
im:6908768
wu:fb55b08
zgc:110752

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have H4 histone acetyltransferase activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Predicted to localize to Piccolo NuA4 histone acetyltransferase complex and nuclear chromatin. Orthologous to human KAT5 (lysine acetyltransferase 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6908768 (1 image)
IMAGE:7140549 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kat5b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with dysmorphic facies, sleep disturbance, and brain abnormalities	619103

Associated With kat5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000953	Chromo/chromo shadow domain
Domain	IPR002717	Histone acetyltransferase domain, MYST-type
Domain	IPR025995	RNA binding activity-knot of a chromodomain
Domain	IPR040706	MYST, zinc finger domain
Homologous_superfamily	IPR016181	Acyl-CoA N-acyltransferase
Homologous_superfamily	IPR016197	Chromo-like domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Acyl-CoA N-acyltransferase	Chromo/chromo shadow domain	Chromo-like domain superfamily	Histone acetyltransferase domain, MYST-type	MYST, zinc finger domain	RNA binding activity-knot of a chromodomain	Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M9Q8J7 InterPro	532
UniProtKB:B8JKI8 InterPro	538
UniProtKB:A0A8M9QDW0 InterPro	555

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	kat5b-201 (1) Ensembl	Havana	2477 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	kat5b-002 (1) Ensembl	Havana	782 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations