ZFIN ID: ZDB-GENE-030131-9828
Gene Name: FtsJ RNA 2'-O-methyltransferase 3
Gene Symbol: ftsj3    Nomenclature History

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Previous Names: ftsj, cb410 (1), sb:cb410, wu:fa08a09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have rRNA (guanine) methyltransferase activity and rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA methylation. Predicted to localize to nucleolus and preribosome, large subunit precursor. Is expressed in several structures, including digestive system; immature eye; mesoderm; midbrain; and musculature system. Orthologous to human FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3).
Genome Resources: Alliance (1),  Gene:321247 (1),  Ensembl(GRCz11):ENSDARG00000104938 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43744 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ftsj3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ftsj3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enzyme-directed rRNA 2'-O-methylation (more)
    Cellular Component nucleus (more)
    Molecular Function methyltransferase activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ftsj3-201 (1)    Ensembl 2641
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ftsj3 No data available
    MARKER RELATIONSHIPS
    ftsj3 Contained in: [Fosmid] CH1073-188M7 (1)
    ftsj3 Encodes: [EST] cb410 (1) (order this), fa08a09
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001305468 (1)
    Genomic GenBank:CU498832 (1) 39129 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IQB8 (1) 838 aa
    Sequence Information (all 13)
    ORTHOLOGY for ftsj3 ( Chr: 22 )
    CITATIONS (19)