Gene
ftsj3
- ID
- ZDB-GENE-030131-9828
- Name
- FtsJ RNA 2'-O-methyltransferase 3
- Symbol
- ftsj3 Nomenclature History
- Previous Names
-
- ftsj
- cb410 (1)
- sb:cb410
- wu:fa08a09
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable rRNA (guanine) methyltransferase activity and rRNA (uridine-2'-O-)-methyltransferase activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and rRNA methylation. Predicted to act upstream of or within RNA methylation and rRNA processing. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in several structures, including digestive system; immature eye; mesoderm; midbrain; and musculature system. Orthologous to human FTSJ3 (FtsJ RNA 2'-O-methyltransferase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb410 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002877 | Ribosomal RNA methyltransferase, FtsJ domain |
| Domain | IPR012920 | Ribosomal RNA methyltransferase, SPB1-like, C-terminal |
| Domain | IPR024576 | Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 |
| Family | IPR015507 | Ribosomal RNA large subunit methyltransferase E |
| Family | IPR028589 | AdoMet-dependent rRNA methyltransferase SPB1-like |
| Family | IPR050082 | Ribosomal RNA large subunit methyltransferase RlmE |
| Homologous_superfamily | IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
Domain Details Per Protein
| Protein | Length | AdoMet-dependent rRNA methyltransferase SPB1-like | Ribosomal RNA large subunit methyltransferase E | Ribosomal RNA large subunit methyltransferase RlmE | Ribosomal RNA methyltransferase, FtsJ domain | Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 | Ribosomal RNA methyltransferase, SPB1-like, C-terminal | S-adenosyl-L-methionine-dependent methyltransferase superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IQB8
|
838 |
Interactions and Pathways
No data available
Plasmids
No data available