Gene

abca1b

ID
ZDB-GENE-030131-9826
Name
ATP-binding cassette, sub-family A (ABC1), member 1B
Symbol
abca1b Nomenclature History
Previous Names
  • im:7136239
  • sb:cb407
  • wu:fa07e06
  • zgc:171581
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled transmembrane transporter activity; phosphatidylcholine floppase activity; and phosphatidylserine floppase activity. Predicted to be involved in phospholipid efflux. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including hypochord; mesoderm; notochord; solid lens vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hypolipoproteinemia (multiple); obesity; and type 2 diabetes mellitus. Orthologous to human ABCA1 (ATP binding cassette subfamily A member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
16 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abca1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Tangier disease Alliance Tangier disease 205400
HDL deficiency, familial, 1 604091
Associated With abca1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017871 ABC transporter, conserved site
Domain IPR003439 ABC transporter-like
Domain IPR003593 AAA+ ATPase domain
Family IPR026082 ABC transporter A
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length AAA+ ATPase domain ABC transporter A ABC transporter, conserved site ABC transporter-like P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A8KB58 142
UniProtKB:F8W2X9 2271
UniProtKB:E7F2Y6 2282
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations