Gene

tpx2

ID

ZDB-GENE-030131-9652

Name

TPX2 microtubule nucleation factor

Symbol

tpx2 Nomenclature History

Previous Names

cb106 (1)
cb340 (1)
fa12d08
sb:cb106
sb:cb340
wu:fa12d08
wu:fb09e10
wu:fc64a03

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to have microtubule binding activity and protein kinase activator activity. Predicted to be involved in mitotic spindle assembly. Predicted to localize to mitotic spindle and nuclear microtubule. Is expressed in proliferative region. Orthologous to human TPX2 (TPX2 microtubule nucleation factor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb106 (7 images)
cb340 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tpx2 Human Ortholog

No data available

Associated With tpx2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR027329	TPX2, C-terminal
Domain	IPR027330	TPX2 central domain
Family	IPR009675	TPX2

Domain Details Per Protein

Protein	Length	TPX2	TPX2 central domain	TPX2, C-terminal
UniProtKB:F1RB66 InterPro	723
UniProtKB:A0A8M6YXL7 InterPro	732
UniProtKB:E9QE51 InterPro	739

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tpx2-201 (1) Ensembl	Ensembl	2576 nt	Select Tool ZFIN BLAST
mRNA	tpx2-205 (1) Ensembl	Havana	2634 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	tpx2-207 (1) Ensembl	Havana	1248 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	tpx2-208 (1) Ensembl	Ensembl	4060 nt	Select Tool ZFIN BLAST
ncRNA	tpx2-003 (1) Ensembl	Havana	1057 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tpx2-004 (1) Ensembl	Havana	693 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tpx2-005 (1) Ensembl	Havana	479 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tpx2-006 (1) Ensembl	Havana	761 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations