Gene
slco3a1a
- ID
- ZDB-GENE-030131-8662
- Name
- solute carrier organic anion transporter family member 3A1a
- Symbol
- slco3a1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in prostaglandin transport and sodium-independent organic anion transport. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Is expressed in several structures, including female organism; gill; liver; pleuroperitoneal region; and skeletal muscle. Orthologous to human SLCO3A1 (solute carrier organic anion transporter family member 3A1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Kazal domain | Kazal domain superfamily | MFS transporter superfamily | Organic anion transporter polypeptide |
|---|---|---|---|---|---|---|
| UniProtKB:Q1LV73 | InterPro | 701 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slco3a1-201
(1)
|
Ensembl | 2,467 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-196L7 | ZFIN Curated Data | |
| Contained in | BAC | DKEYP-59C12 | ZFIN Curated Data | |
| Encodes | EST | fa93e11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045188 (1) | 2106 nt | ||
| Genomic | GenBank:BX649578 (1) | 211922 nt | ||
| Polypeptide | UniProtKB:Q1LV73 (1) | 701 aa |
- Lu, X., Tian, J., Wen, H., Jiang, M., Liu, W., Wu, F., Yu, L., Zhong, S. (2019) Microcystin-LR-regulated transcriptome dynamics in ZFL cells. Aquatic toxicology (Amsterdam, Netherlands). 212:222-232
- Newman, M., Hin, N., Pederson, S., Lardelli, M. (2019) Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Molecular brain. 12:43
- Foulkes, M.J., Henry, K.M., Rougeot, J., Hooper-Greenhill, E., Loynes, C.A., Jeffrey, P., Fleming, A., Savage, C.O., Meijer, A.H., Jones, S., Renshaw, S.A. (2017) Expression and regulation of drug transporters in vertebrate neutrophils. Scientific Reports. 7:4967
- Jantzen, C.E., Toor, F., Annunziato, K.A., Cooper, K.R. (2017) Effects of Chronic Perfluorooctanoic Acid (PFOA) at Low Concentration on Morphometrics, Gene Expression, and Fecundity in Zebrafish (Danio rerio). Reproductive toxicology (Elmsford, N.Y.). 69:34-42
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Liu, L., Li, Y., Coelhan, M., Chan, H.M., Ma, W., Liu, L. (2016) Relative developmental toxicity of short-chain chlorinated paraffins in Zebrafish (Danio rerio) embryos. Environmental pollution (Barking, Essex : 1987). 219:1122-1130
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Muzzio, A.M., Noyes, P.D., Stapleton, H.M., Lema, S.C. (2014) Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 167:77-89
- Popovic, M., Zaja, R., and Smital, T. (2010) Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): Phylogenetic analysis and tissue distribution. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 155(3):327-335
- Cañestro, C., Catchen, J.M., Rodriguez-Mari, A., Yokoi, H., and Postlethwait, J.H. (2009) Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. PLoS Genetics. 5(5):e1000496
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