Gene

si:ch211-1i11.3

ID

ZDB-GENE-030131-8638

Name

si:ch211-1i11.3

Symbol

si:ch211-1i11.3 Nomenclature History

Previous Names

fa92h04
wu:fa92h04 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in JNK cascade and p38MAPK cascade. Predicted to act upstream of or within MAPK cascade and protein phosphorylation. Orthologous to human MAP3K6 (mitogen-activated protein kinase kinase kinase 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With si:ch211-1i11.3 Human Ortholog

No data available

Associated With si:ch211-1i11.3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR025136	MAP3K, TRAFs-binding domain
Domain	IPR043969	MAP3K, PH domain
Domain	IPR046872	MAP3K, deoxyribohydrolase domain
Domain	IPR046873	MAP3K, HisK-N-like globin domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	MAP3K, deoxyribohydrolase domain	MAP3K, HisK-N-like globin domain	MAP3K, PH domain	MAP3K, TRAFs-binding domain	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:A0A2R8QB27 InterPro	1324
UniProtKB:A0A8M9Q201 InterPro	1239
UniProtKB:A0A8M9P8E9 InterPro	1240

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:ch211-1i11.3-201 (1) Ensembl	Ensembl	3,474 nt	Select Tool ZFIN BLAST
mRNA	si:ch211-1i11.3-202 (1) Ensembl	Ensembl	3,522 nt	Select Tool ZFIN BLAST
mRNA	si:ch211-1i11.3-203 (1) Ensembl	Ensembl	4,922 nt	Select Tool ZFIN BLAST
mRNA	si:ch211-1i11.3-204 (1) Ensembl	Ensembl	5,015 nt	Select Tool ZFIN BLAST
mRNA	si:ch211-1i11.3-205 (1) Ensembl	Ensembl	4,919 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations