Gene
gprc5ba
- ID
- ZDB-GENE-030131-8162
- Name
- G protein-coupled receptor, class C, group 5, member Ba
- Symbol
- gprc5ba Nomenclature History
- Previous Names
-
- gprc5b
- wu:fj56g04
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable protein kinase activator activity and protein kinase binding activity. Acts upstream of or within lymph vessel development. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in extracellular exosome; intracellular membrane-bounded organelle; and plasma membrane. Human ortholog(s) of this gene implicated in megalencephalic leukoencephalopathy with subcortical cysts. Orthologous to human GPRC5B (G protein-coupled receptor class C group 5 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Greenhough et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Xu et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Megalencephalic leukoencephalopathy with subcortical cysts 3 | 620447 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR family 3, C-terminal | Retinoic acid-inducible GPCR family 3 |
|---|---|---|---|
|
UniProtKB:X1WEL2
|
397 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
gprc5ba-201
(1)
|
Ensembl | 2,087 nt |
Interactions and Pathways
No data available
Plasmids
No data available