Gene
twf2a
- ID
- ZDB-GENE-030131-7638
- Name
- twinfilin actin-binding protein 2a
- Symbol
- twf2a Nomenclature History
- Previous Names
-
- twf1l
- ptk9l (1)
- zgc:91817
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in actin filament depolymerization; barbed-end actin filament capping; and regulation of plasma membrane bounded cell projection organization. Predicted to act upstream of or within negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton and perinuclear region of cytoplasm. Predicted to be active in actin filament and myofibril. Is expressed in lateral line ganglion; myotome; pectoral fin musculature; pharyngeal arch; and somite.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:91817 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-depolymerising factor homology domain | ADF-H/Gelsolin-like domain superfamily | Twinfilin |
|---|---|---|---|---|
|
UniProtKB:Q6GMH3
|
347 | |||
|
UniProtKB:A0A8M2BDE1
|
352 |
Interactions and Pathways
No data available
Plasmids
No data available