Gene

tesk1b

ID

ZDB-GENE-030131-7512

Name

testis associated actin remodelling kinase 1b

Symbol

tesk1b Nomenclature History

Previous Names

fj22e11
si:dkeyp-75h12.2
wu:fj22e11 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human TESK1 (testis associated actin remodelling kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tesk1b Human Ortholog

No data available

Associated With tesk1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008266	Tyrosine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
Family	IPR050940	Actin-regulating Serine/Threonine Kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	Actin-regulating Serine/Threonine Kinase	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine-threonine/tyrosine-protein kinase, catalytic domain	Tyrosine-protein kinase, active site
UniProtKB:E7FEW6	InterPro	653

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:dkeyp-75h12.2-201 (1) Ensembl	Ensembl	2,859 nt	Select Tool ZFIN BLAST
mRNA	tesk1-203 (1) Ensembl	Ensembl	3,281 nt	Select Tool ZFIN BLAST
ncRNA	si:dkeyp-75h12.2-002 (1) Ensembl	Ensembl	787 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations