tanc2b

ID

ZDB-GENE-030131-7067

Name

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2b

Symbol

tanc2b Nomenclature History

Previous Names

fk73b01
wu:fk73b01 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within several processes, including behavioral fear response; sleep; and social behavior. Predicted to be located in postsynapse. Predicted to be active in dendritic spine. Is expressed in central nervous system. Human ortholog(s) of this gene implicated in intellectual developmental disorder with autistic features and language delay, with or without seizures. Orthologous to human TANC2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Long et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tanc2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
intellectual developmental disorder with autistic features and language delay, with or without seizures	Alliance	Intellectual developmental disorder with autistic features and language delay, with or without seizures	618906

Associated With tanc2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:F1R409	InterPro	1720
UniProtKB:A0A8M6Z3J5	InterPro	2164
UniProtKB:A0AC58GWN3	InterPro	2153
UniProtKB:A0AC58GWN4	InterPro	2164
UniProtKB:A0AC58GWN5	InterPro	2141
UniProtKB:A0AC58GWN6	InterPro	2152
UniProtKB:A0AC58GWN7	InterPro	2152
UniProtKB:A0AC58GWN8	InterPro	2141
UniProtKB:A0AC58GWP5	InterPro	2090
UniProtKB:A0AC58GWP6	InterPro	2059
UniProtKB:A0AC58GWP7	InterPro	2164
UniProtKB:A0AC58GWP8	InterPro	2047
UniProtKB:A0AC58GWP9	InterPro	2078
UniProtKB:A0AC58GWQ0	InterPro	2036
UniProtKB:A0AC58GWQ1	InterPro	2079
UniProtKB:A0AC58GWQ5	InterPro	2010
UniProtKB:A0AC58GWQ7	InterPro	1902
UniProtKB:A0AC58GWQ8	InterPro	1925
UniProtKB:A0AC58GWR2	InterPro	2067
UniProtKB:A0AC58GWR8	InterPro	2021
UniProtKB:A0AC58GWS5	InterPro	2033