ZFIN is now using GRCz12tu for Genomic Data
Gene
rin2b
- ID
- ZDB-GENE-030131-7043
- Name
- Ras and Rab interactor 2b
- Symbol
- rin2b Nomenclature History
- Previous Names
-
- fk68e06
- si:ch211-85n16.4
- wu:fk68e06 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be located in cytoplasm. Predicted to be active in cytosol and endocytic vesicle. Orthologous to human RIN2 (Ras and Rab interactor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Macrocephaly, alopecia, cutis laxa, and scoliosis | 613075 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000980 | SH2 domain |
| Domain | IPR003123 | VPS9 domain |
| Domain | IPR035868 | Ras and Rab interactor 2, SH2 domain |
| Family | IPR045046 | Vacuolar protein sorting-associated protein 9-like |
| Homologous_superfamily | IPR036860 | SH2 domain superfamily |
| Homologous_superfamily | IPR037191 | VPS9 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ras and Rab interactor 2, SH2 domain | Ras-associating domain | SH2 domain | SH2 domain superfamily | Vacuolar protein sorting-associated protein 9-like | VPS9 domain | VPS9 domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z153 | InterPro | 567 | |||||||
| UniProtKB:A0A8M6YZM7 | InterPro | 899 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rin2-203
(1)
|
Ensembl | 1,359 nt | ||
| mRNA |
si:ch211-85n16.4-201
(1)
|
Ensembl | 2,475 nt | ||
| ncRNA |
si:ch211-85n16.4-002
(1)
|
Ensembl | 487 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance