Gene
banf1
- ID
- ZDB-GENE-030131-6657
- Name
- barrier to autointegration nuclear assembly factor 1
- Symbol
- banf1 Nomenclature History
- Previous Names
-
- fa01c01
- wu:fa01c01
- zgc:77767
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable DNA binding activity. Predicted to be involved in several processes, including mitotic nuclear membrane reassembly; negative regulation of type I interferon production; and response to oxidative stress. Predicted to be located in chromatin. Predicted to be active in condensed chromosome and nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in Nestor-Guillermo progeria syndrome. Orthologous to human BANF1 (barrier to autointegration nuclear assembly factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Nestor-Guillermo progeria syndrome | Alliance | Nestor-Guillermo progeria syndrome | 614008 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Barrier-to-autointegration factor | Barrier- to-autointegration factor, BAF | Barrier-to-autointegration factor, BAF superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6P026
|
90 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available