Gene

zgc:173742

ID
ZDB-GENE-030131-6489
Name
zgc:173742
Symbol
zgc:173742 Nomenclature History
Previous Names
  • fl27b11
  • si:dkey-204j6.1
  • wu:fl27b11 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable DNA topoisomerase type I (single strand cut, ATP-independent) activity. Predicted to be involved in DNA replication; DNA topological change; and chromosome segregation. Predicted to be located in chromosome. Predicted to be active in nucleolus.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa44884Allele with one point mutationUnknownUnknownENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With zgc:173742 Human Ortholog
No data available
Associated With zgc:173742 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018521 DNA topoisomerase I, active site
Domain IPR008336 DNA topoisomerase I, DNA binding, eukaryotic-type
Domain IPR013499 DNA topoisomerase I, eukaryotic-type
Domain IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type
Domain IPR025834 Topoisomerase I C-terminal domain
1 - 5 of 14 Show all
Domain Details Per Protein
Protein Additional Resources Length DNA breaking-rejoining enzyme, catalytic core DNA topoisomerase I DNA topoisomerase I, active site DNA topoisomerase IB DNA topoisomerase I, catalytic core, alpha/beta subdomain DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type DNA topoisomerase I, catalytic core, eukaryotic-type DNA topoisomerase I, DNA-binding domain DNA topoisomerase I, DNA binding, eukaryotic-type DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily DNA topoisomerase I, DNA binding, N-terminal domain 1 DNA topoisomerase I, DNA binding, N-terminal domain 2 DNA topoisomerase I, eukaryotic-type Topoisomerase I C-terminal domain
UniProtKB:A0A8M2BH93 InterPro 735
UniProtKB:A0A8M9PVS7 InterPro 735
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 18
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA zgc:173742-201 (1)
Ensembl
Ensembl 1,941 nt
ZFIN BLAST
mRNA zgc:173742-202 (1)
Ensembl
Ensembl 673 nt
ZFIN BLAST
mRNA zgc:173742-203 (1)
Ensembl
Ensembl 1,449 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-204J6ZFIN Curated Data
EncodesESTfl27b11
Has ArtifactcDNAMGC:173742ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_021473248 (1)3815 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CU424459 (1)94918 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M2BH93 (1)735 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
No data available
Your Input Welcome
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