Gene
cenpj
- ID
- ZDB-GENE-030131-6323
- Name
- centromere protein J
- Symbol
- cenpj Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have tubulin binding activity. Predicted to be involved in centriole elongation and cilium assembly. Predicted to localize to centriole; centrosome; and nucleus. Human ortholog(s) of this gene implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6. Orthologous to human CENPJ (centromere protein J).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary autosomal recessive microcephaly 6 | Alliance | Microcephaly 6, primary, autosomal recessive | 608393 |
| Seckel syndrome 4 | Alliance | ?Seckel syndrome 4 | 613676 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Centromere protein J, C-terminal domain | T-complex protein 10, C-terminal domain superfamily | T-complex protein 10 family |
|---|---|---|---|---|
|
UniProtKB:E7FCY1
|
1124 |
Interactions and Pathways
No data available
Plasmids
No data available