Gene
arap1a
- ID
- ZDB-GENE-030131-6226
- Name
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1a
- Symbol
- arap1a Nomenclature History
- Previous Names
-
- fi39f07
- si:ch211-135f11.1 (1)
- wu:fi39f07
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in regulation of actin cytoskeleton organization and regulation of cell projection organization. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be active in cytoplasm. Orthologous to human ARAP1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000198 | Rho GTPase-activating protein domain |
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR037858 | ARAP, RhoGAP domain |
| Family | IPR052227 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein |
| Homologous_superfamily | IPR008936 | Rho GTPase activation protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
Domain Details Per Protein
| Protein | Length | ARAP, RhoGAP domain | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein | Arf GTPase activating protein | PH-like domain superfamily | Pleckstrin homology domain | Ras-associating domain | Rho GTPase-activating protein domain | Rho GTPase activation protein |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6YYD8
|
696 | ||||||||||
|
UniProtKB:A0A8M9PYK7
|
1091 | ||||||||||
|
UniProtKB:A0A8N7TBX5
|
1092 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arap1a-201
(1)
|
Ensembl | 3,445 nt |
Interactions and Pathways
No data available
Plasmids
No data available