Gene
tdo2b
- ID
- ZDB-GENE-030131-6014
- Name
- tryptophan 2,3-dioxygenase b
- Symbol
- tdo2b Nomenclature History
- Previous Names
-
- tdo2l
- fi30d08
- wu:fi30d08
- zgc:63488 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to have heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in protein homotetramerization; tryptophan catabolic process to acetyl-CoA; and tryptophan catabolic process to kynurenine. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Is expressed in gut and liver. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63488 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tryptophan 2,3-dioxygenase | Tryptophan/Indoleamine 2,3-dioxygenase-like |
|---|---|---|---|
|
UniProtKB:Q7SY53
|
407 | ||
|
UniProtKB:A0A8M9QCY2
|
403 |
Interactions and Pathways
No data available
Plasmids
No data available