Gene
tdo2b
- ID
- ZDB-GENE-030131-6014
- Name
- tryptophan 2,3-dioxygenase b
- Symbol
- tdo2b Nomenclature History
- Previous Names
-
- tdo2l
- fi30d08
- wu:fi30d08
- zgc:63488 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable heme binding activity and tryptophan 2,3-dioxygenase activity. Predicted to be involved in L-tryptophan catabolic process to acetyl-CoA; L-tryptophan catabolic process to kynurenine; and protein homotetramerization. Predicted to act upstream of or within L-tryptophan catabolic process. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and familial hypertryptophanemia. Orthologous to human TDO2 (tryptophan 2,3-dioxygenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63488 (2 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tryptophan 2,3-dioxygenase | Tryptophan/Indoleamine 2,3-dioxygenase-like |
|---|---|---|---|
|
UniProtKB:Q7SY53
|
407 | ||
|
UniProtKB:A0A8M9QCY2
|
403 |
Interactions and Pathways
No data available
Plasmids
No data available