Gene

prx

ID

ZDB-GENE-030131-5790

Name

periaxin

Symbol

prx Nomenclature History

Previous Names

fi18g02
im:7153437
si:ch211-14c7.3
wu:fi18g02 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to be involved in regulation of RNA splicing. Predicted to localize to cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 3 and Charcot-Marie-Tooth disease type 4F. Orthologous to human PRX (periaxin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prx Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Charcot-Marie-Tooth disease type 3	Alliance	Dejerine-Sottas disease	145900
Charcot-Marie-Tooth disease type 4F	Alliance	Charcot-Marie-Tooth disease, type 4F	614895

Associated With prx Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	PDZ domain	PDZ superfamily
UniProtKB:A0A8M9PR13 InterPro	3878
UniProtKB:A0A8M9PAK8 InterPro	3942
UniProtKB:A0A8M9PAL3 InterPro	3939
UniProtKB:A0A8M9P1I2 InterPro	3939
UniProtKB:A0A8M6YUC8 InterPro	4061
UniProtKB:A0A8M9PG02 InterPro	3942
UniProtKB:A0A8M9P1I6 InterPro	3702
UniProtKB:A0A8M9PAM0 InterPro	2484
UniProtKB:A0A8M9P1H8 InterPro	3959
UniProtKB:A0A8M9PG08 InterPro	3939
UniProtKB:A0A8M9PG11 InterPro	3637
UniProtKB:A0A8M9PR18 InterPro	3213
UniProtKB:A0A8M9PMS1 InterPro	3820
UniProtKB:A0A8M9P1I9 InterPro	2542
UniProtKB:A0A8M9PMR4 InterPro	3942
UniProtKB:A0A8M6Z2U4 InterPro	3152
UniProtKB:A0A8M9PMQ8 InterPro	4000
UniProtKB:A0A8M9PR08 InterPro	3942
UniProtKB:A0A8M9PMS5 InterPro	2850
UniProtKB:A0A8M6YW83 InterPro	3695

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	prx-201 (1) Ensembl	Havana	2247 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	prx-202 (1) Ensembl	Havana	772 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations