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Gene

cox4i1

ID
ZDB-GENE-030131-5175
Name
cytochrome c oxidase subunit 4I1
Symbol
cox4i1 Nomenclature History
Previous Names
  • Cox4-1 (1)
  • mg:bb02d03
  • zgc:110058
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable cytochrome-c oxidase activity. Acts upstream of or within response to hypoxia. Predicted to be located in membrane and mitochondrion. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including adaxial cell; brain; digestive system; eye; and muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to several human genes including COX4I1 (cytochrome c oxidase subunit 4I1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox4i1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Mitochondrial complex IV deficiency, nuclear type 16 619060
Associated With cox4i1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004203 Cytochrome c oxidase subunit IV family
Family IPR013288 Cytochrome c oxidase subunit IV
Homologous_superfamily IPR036639 Cytochrome c oxidase subunit IV superfamily
Domain Details Per Protein
Protein Length Cytochrome c oxidase subunit IV Cytochrome c oxidase subunit IV family Cytochrome c oxidase subunit IV superfamily
UniProtKB:Q6TNV0 169
UniProtKB:Q4VBT9 169
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations