Gene
cox4i1
- ID
- ZDB-GENE-030131-5175
- Name
- cytochrome c oxidase subunit 4I1
- Symbol
- cox4i1 Nomenclature History
- Previous Names
-
- Cox4-1 (1)
- mg:bb02d03
- zgc:110058
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable oxidoreductase activity. Predicted to contribute to cytochrome-c oxidase activity. Acts upstream of or within response to hypoxia. Predicted to be located in membrane and mitochondrion. Predicted to be part of mitochondrial respiratory chain complex IV. Is expressed in several structures, including adaxial cell; brain; digestive system; eye; and muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX4I1 (cytochrome c oxidase subunit 4I1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110058 (1 image)
- IMAGE:6899294 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 16 | Alliance | Mitochondrial complex IV deficiency, nuclear type 16 | 619060 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase subunit IV | Cytochrome c oxidase subunit IV family | Cytochrome c oxidase subunit IV superfamily |
|---|---|---|---|---|
|
UniProtKB:Q6TNV0
|
169 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cox4i1-201
(1)
|
Ensembl | 709 nt | ||
| mRNA |
cox4i1-202
(1)
|
Ensembl | 512 nt |
Interactions and Pathways
No data available
Plasmids
No data available