Gene
zbtb11
- ID
- ZDB-GENE-030131-5055
- Name
- zinc finger and BTB domain containing 11
- Symbol
- zbtb11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in neutrophil differentiation. Predicted to localize to nucleus. Is expressed in head; intermediate cell mass of mesoderm; and nervous system. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ZBTB11 (zinc finger and BTB domain containing 11).
- Genome Resources
- Note
- None
- All Expression Data
- from Keightley et al., 2017
- Cross-Species Comparison
- High Throughput Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Keightley et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, autosomal recessive 69 | 618383 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Integrase zinc-binding domain | SKP1/BTB/POZ domain superfamily | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
|
UniProtKB:Q5PNQ0
|
199 | |||||
|
UniProtKB:F1RAC1
|
1146 | |||||
|
UniProtKB:Q6TNP6
|
262 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
zbtb11-202
(1)
|
4090 nt | |
| ncRNA |
zbtb11-002
(1)
|
1425 nt |
Interactions and Pathways
No data available
Plasmids
No data available