ZFIN ID: ZDB-GENE-030131-5055
Gene Name: zinc finger and BTB domain containing 11
Gene Symbol: zbtb11    Nomenclature History

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Previous Names: man, marsanne (1), mne, si:dkey-98p3.1, si:dkeyp-116g9.2, wu:fc06h02, wu:fe36e08 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in neutrophil differentiation. Predicted to localize to nucleus. Is expressed in head; intermediate cell mass of mesoderm; and nervous system. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ZBTB11 (zinc finger and BTB domain containing 11).
Genome Resources: Alliance (1),  Gene:555217 (1),  Ensembl(GRCz11):ENSDARG00000017886 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
gl11 Point Mutation Unknown Missense ENU
gl12 Complex Unknown Unknown CRISPR
sa2282 Point Mutation Unknown Splice Site ENU
sa14905 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17282 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-zbtb11 1
    MO1-zbtb11 N/A 1
    DISEASE ASSOCIATED WITH zbtb11 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Intellectual developmental disorder, autosomal recessive 69 618383
    DISEASE ASSOCIATED WITH zbtb11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neutrophil differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zbtb11-202 (1)    Ensembl 4090
    ncRNA zbtb11-002 (1)    Ensembl 1425
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zbtb11 No data available
    MARKER RELATIONSHIPS
    zbtb11 Contained in: [BAC] DKEYP-116G9 (1)
    zbtb11 Contains: [SNP] rs3727977 (1), rs3727978 (1), rs3727979 (1)
    zbtb11 Encodes: [EST] fc06h02, fe36e08
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212650 (1) 1431 nt
    Genomic GenBank:BX571699 (1) 173467 nt
    Select Tool
    Polypeptide UniProtKB:F1RAC1 (1) 1146 aa
    Sequence Information (all 17)
    ORTHOLOGY for zbtb11 ( Chr: 6 )
    CITATIONS (23)