Gene

mhc2d4b

ID

ZDB-GENE-030131-4747

Name

major histocompatibility complex class II d4b

Symbol

mhc2d4b Nomenclature History

Previous Names

D4B (1)
si:ch73-158p21.3 (1)
wu:fd58b11 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to be involved in antigen processing and presentation and immune response. Predicted to localize to MHC class II protein complex. Orthologous to human HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2005

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu457 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mhc2d4b Human Ortholog

No data available

Associated With mhc2d4b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000353	MHC class II, beta chain, N-terminal
Domain	IPR003597	Immunoglobulin C1-set
Domain	IPR007110	Immunoglobulin-like domain
Family	IPR050160	Major Histocompatibility Complex/Immunoglobulin
Homologous_superfamily	IPR011162	MHC classes I/II-like antigen recognition protein
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014745	MHC class II, alpha/beta chain, N-terminal
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin C1-set	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Major Histocompatibility Complex/Immunoglobulin	MHC classes I/II-like antigen recognition protein	MHC class II, alpha/beta chain, N-terminal	MHC class II, beta chain, N-terminal
UniProtKB:A0A1L1QZR0 InterPro	249
UniProtKB:A0A8M1RH77 InterPro	248

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	si:ch73-158p21.3-201 (1) Ensembl	Ensembl	738 nt	Select Tool ZFIN BLAST
mRNA	si:ch73-158p21.3-202 (1) Ensembl	Ensembl	2,343 nt	Select Tool
ncRNA	si:ch73-158p21.3-002 (1) Ensembl	Ensembl	764 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations