Gene
habp2
- ID
- ZDB-GENE-030131-4721
- Name
- hyaluronan binding protein 2
- Symbol
- habp2 Nomenclature History
- Previous Names
-
- fd56a04
- wu:fd56a04 (1)
- zgc:171352
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in thrombophilia due to thrombin defect and thyroid gland papillary carcinoma. Orthologous to human HABP2 (hyaluronan binding protein 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
prothrombin thrombophilia | Alliance | {Venous thromboembolism, susceptibility to} | 188050 |
thrombophilia due to thrombin defect | Alliance | {Venous thromboembolism, susceptibility to} | 188050 |
{?Thyroid cancer, nonmedullary, 5} | 616535 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR018114 | Serine proteases, trypsin family, histidine active site |
Active_site | IPR033116 | Serine proteases, trypsin family, serine active site |
Conserved_site | IPR018056 | Kringle, conserved site |
Domain | IPR000001 | Kringle |
Domain | IPR000742 | EGF-like domain |
Domain | IPR001254 | Serine proteases, trypsin domain |
Domain | IPR001881 | EGF-like calcium-binding domain |
Family | IPR001314 | Peptidase S1A, chymotrypsin family |
Family | IPR012224 | Peptidase S1A, coagulation factor VII/IX/X/C/Z |
Family | IPR050127 | Serine Proteases (Peptidase S1 Family) |
Homologous_superfamily | IPR009003 | Peptidase S1, PA clan |
Homologous_superfamily | IPR013806 | Kringle-like fold |
Homologous_superfamily | IPR038178 | Kringle superfamily |
Homologous_superfamily | IPR043504 | Peptidase S1, PA clan, chymotrypsin-like fold |
Domain Details Per Protein
Protein | Length | EGF-like calcium-binding domain | EGF-like domain | Kringle | Kringle, conserved site | Kringle-like fold | Kringle superfamily | Peptidase S1A, chymotrypsin family | Peptidase S1A, coagulation factor VII/IX/X/C/Z | Peptidase S1, PA clan | Peptidase S1, PA clan, chymotrypsin-like fold | Serine Proteases (Peptidase S1 Family) | Serine proteases, trypsin domain | Serine proteases, trypsin family, histidine active site | Serine proteases, trypsin family, serine active site |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QW52
|
546 |
Interactions and Pathways
No data available
Plasmids
No data available