Gene

c1s.2

ID
ZDB-GENE-030131-4645
Name
complement component 1, s subcomponent .2
Symbol
c1s.2 Nomenclature History
Previous Names
  • fd46c06
  • wu:fd46c06 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase activity. Predicted to act upstream of or within complement activation, classical pathway and proteolysis. Predicted to be active in extracellular space. Orthologous to human C1RL (complement C1r subcomponent like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa17822Allele with one point mutationUnknownSplice SiteENU
sa22881Allele with one point mutationUnknownPremature StopENU
sa28691Allele with one point mutationUnknownSplice SiteENU
sa36184Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With c1s.2 Human Ortholog
No data available
Associated With c1s.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000859 CUB domain
Domain IPR001254 Serine proteases, trypsin domain
Family IPR001314 Peptidase S1A, chymotrypsin family
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Domain Details Per Protein
Protein Length CUB domain Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, serine active site Spermadhesin, CUB domain superfamily Sushi/SCR/CCP domain
UniProtKB:A9JSU2 458
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Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA c1s.2-201 (1) Ensembl 1,624 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
EncodesESTfd46c06
EncodescDNAMGC:171527ZFIN Curated Data
Is Hybridized byESTfb57b02
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Sequences
Orthology
Comparative Orthology
Alliance
Citations
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