Gene
tmem260
- ID
- ZDB-GENE-030131-4198
- Name
- transmembrane protein 260
- Symbol
- tmem260 Nomenclature History
- Previous Names
-
- fc80c01
- wu:fc80c01
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable dolichyl-phosphate-mannose-protein mannosyltransferase activity. Acts upstream of or within central nervous system development. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in T-cell non-Hodgkin lymphoma; non-Hodgkin lymphoma; and stomach cancer. Orthologous to human TMEM260 (transmembrane protein 260).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Ta-Shma et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Structural heart defects and renal anomalies syndrome | 617478 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glycosyltransferase 117 domain-containing protein | Protein O-mannosyl-transferase TMEM260-like |
|---|---|---|---|---|
| UniProtKB:A0A8M3AUJ3 | InterPro | 652 | ||
| UniProtKB:A0A8M9PLK5 | InterPro | 683 | ||
| UniProtKB:E7F5M2 | InterPro | 684 | ||
| UniProtKB:A0AB32T4B4 | InterPro | 652 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tmem260-201
(1)
|
Ensembl | 3,526 nt | ||
| mRNA |
tmem260-202
(1)
|
Ensembl | 6,333 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance