trim37

ID

ZDB-GENE-030131-2957

Name

tripartite motif containing 37

Symbol

trim37 Nomenclature History

Previous Names

fc22d08
si:ch211-251d10.4
wu:fc22d08 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable tumor necrosis factor receptor binding activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Predicted to be involved in aggresome assembly; protein autoubiquitination; and protein monoubiquitination. Predicted to be located in cytoplasm. Predicted to be active in aggresome and peroxisomal membrane. Human ortholog(s) of this gene implicated in mulibrey nanism. Orthologous to human TRIM37 (tripartite motif containing 37).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trim37 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
mulibrey nanism	Alliance	Mulibrey nanism	253250

Associated With trim37 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000315	B-box-type zinc finger
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR002083	MATH/TRAF domain
Domain	IPR003649	B-box, C-terminal
Domain	IPR037299	TRIM37, MATH domain
Family	IPR053003	TRIM/RBCC E3 ubiquitin-protein ligases
Homologous_superfamily	IPR008974	TRAF-like
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type