Gene
trim37
- ID
- ZDB-GENE-030131-2957
- Name
- tripartite motif containing 37
- Symbol
- trim37 Nomenclature History
- Previous Names
-
- fc22d08
- si:ch211-251d10.4
- wu:fc22d08 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable tumor necrosis factor receptor binding activity; ubiquitin protein ligase activity; and ubiquitin protein ligase binding activity. Predicted to be involved in aggresome assembly; protein autoubiquitination; and protein monoubiquitination. Predicted to act upstream of or within protein ubiquitination. Predicted to be part of ESC/E(Z) complex. Predicted to be active in aggresome and peroxisomal membrane. Human ortholog(s) of this gene implicated in mulibrey nanism. Orthologous to human TRIM37 (tripartite motif containing 37).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mulibrey nanism | Alliance | Mulibrey nanism | 253250 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000315 | B-box-type zinc finger |
| Domain | IPR001841 | Zinc finger, RING-type |
| Domain | IPR002083 | MATH/TRAF domain |
| Domain | IPR003649 | B-box, C-terminal |
| Domain | IPR037299 | TRIM37, MATH domain |
| Family | IPR053003 | TRIM/RBCC E3 ubiquitin-protein ligases |
| Homologous_superfamily | IPR008974 | TRAF-like |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
| Protein | Additional Resources | Length | B-box, C-terminal | B-box-type zinc finger | MATH/TRAF domain | TRAF-like | TRIM37, MATH domain | TRIM/RBCC E3 ubiquitin-protein ligases | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FBZ8 | InterPro | 957 | ||||||||
| UniProtKB:A0A8M9PU88 | InterPro | 952 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trim37-201
(1)
|
Ensembl | 4,732 nt |
Interactions and Pathways
No data available
Plasmids
No data available