Gene

cfbl

ID
ZDB-GENE-030131-2319
Name
complement factor b, like
Symbol
cfbl Nomenclature History
Previous Names
  • fc04c04
  • wu:fc04c04
  • zgc:158446 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase activity. Acts upstream of or within response to bacterium. Predicted to be located in extracellular region. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; autoimmune disease (multiple); eye disease (multiple); glomerulonephritis (multiple); and sickle cell anemia. Orthologous to human CFB (complement factor B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Meijer et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cfbl Human Ortholog
No data available
Associated With cfbl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR001254 Serine proteases, trypsin domain
Domain IPR002035 von Willebrand factor, type A
Family IPR001314 Peptidase S1A, chymotrypsin family
1 - 5 of 10 Show all
Domain Details Per Protein
Protein Additional Resources Length Complement B/C2 Peptidase S1A, chymotrypsin family Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:A2VD28 InterPro 751
1 - 1 of 1
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cfbl-201 (1)
Ensembl
Ensembl 2,575 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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