ZFIN is now using GRCz12tu for Genomic Data

Gene

tlcd3ba

ID

ZDB-GENE-030131-2046

Name

TLC domain containing 3Ba

Symbol

tlcd3ba Nomenclature History

Previous Names

fam57ba
fb95d07
wu:fb95d07
zgc:73225

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable sphingosine N-acyltransferase activity. Acts upstream of or within several processes, including central nervous system development; lipid homeostasis; and startle response. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in brain; central nervous system; epiphysis; head; and neurons. Human ortholog(s) of this gene implicated in cone-rod dystrophy 22. Orthologous to human TLCD3B (TLC domain containing 3B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:73225 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tlcd3ba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
cone-rod dystrophy 22	Alliance	Cone-rod dystrophy 22	619531

Associated With tlcd3ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006634	TRAM/LAG1/CLN8 homology domain
Family	IPR050846	TLC domain-containing

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:X1WH51	InterPro	193
UniProtKB:A0A8M2BB48	InterPro	161
UniProtKB:Q6PBV7	InterPro	242
UniProtKB:A0A8M2BBE5	InterPro	292

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fam57ba-202 (1) Ensembl	Ensembl	745 nt	Select Tool ZFIN BLAST
mRNA	fam57ba-203 (1) Ensembl	Ensembl	923 nt	Select Tool ZFIN BLAST
mRNA	fam57ba-204 (1) Ensembl	Ensembl	886 nt	Select Tool ZFIN BLAST
mRNA	fam57ba-205 (1) Ensembl	Ensembl	911 nt	Select Tool ZFIN BLAST
mRNA	fam57ba-206 (1) Ensembl	Ensembl	891 nt	Select Tool ZFIN BLAST
mRNA	fam57ba-208 (1) Ensembl	Ensembl	1,382 nt	Select Tool ZFIN BLAST
mRNA	tlcd3ba-201 (1) Ensembl	Ensembl	1,141 nt	Select Tool ZFIN BLAST
ncRNA	fam57ba-007 (1) Ensembl	Ensembl	680 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations