Gene

alox12

ID
ZDB-GENE-030131-1452
Name
arachidonate 12-lipoxygenase
Symbol
alox12 Nomenclature History
Previous Names
  • ALOX1 (1)
  • LOX1 (1)
  • wu:fb72a11
  • zgc:64120
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Exhibits arachidonate 12(S)-lipoxygenase activity and calcium ion binding activity. Involved in oxidation-reduction process. Localizes to nucleus. Is expressed in several structures, including EVL; digestive system; epidermal cell; epidermis; and periderm. Orthologous to several human genes including ALOX12 (arachidonate 12-lipoxygenase, 12S type).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Haas et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alox12 Human Ortholog
No data available
Associated With alox12 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020834 Lipoxygenase, conserved site
Domain IPR001024 PLAT/LH2 domain
Domain IPR013819 Lipoxygenase, C-terminal
Domain IPR042062 Lipoxygenase, vertebrates, PLAT domain
Family IPR000907 Lipoxygenase
Family IPR001885 Lipoxygenase, mammalian
Homologous_superfamily IPR036226 Lipoxigenase, C-terminal domain superfamily
Homologous_superfamily IPR036392 PLAT/LH2 domain superfamily
Domain Details Per Protein
Protein Length Lipoxigenase, C-terminal domain superfamily Lipoxygenase Lipoxygenase, conserved site Lipoxygenase, C-terminal Lipoxygenase, mammalian Lipoxygenase, vertebrates, PLAT domain PLAT/LH2 domain PLAT/LH2 domain superfamily
UniProtKB:Q7T2A9 670
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations