Gene

c1s.1

ID
ZDB-GENE-030131-1232
Name
complement component 1, s subcomponent .1
Symbol
c1s.1 Nomenclature History
Previous Names
  • c1s (1)
  • wu:fb63d09
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome. Orthologous to human C1S (complement C1s).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With c1s.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
C1s deficiency 613783
Ehlers-Danlos syndrome, periodontal type, 2 617174
Associated With c1s.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000742 EGF-like domain
Domain IPR000859 CUB domain
Domain IPR001881 EGF-like calcium-binding domain
Homologous_superfamily IPR035914 Spermadhesin, CUB domain superfamily
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length CUB domain EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Spermadhesin, CUB domain superfamily Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:A0A0G2KTB7 375
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations