Gene

kat6a

ID
ZDB-GENE-021022-3
Name
K(lysine) acetyltransferase 6A
Symbol
kat6a Nomenclature History
Previous Names
  • bmd (1)
  • monocytic leukemia zinc finger
  • moz (1)
  • myst3
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits histone acetyltransferase activity. Involved in several processes, including embryonic body morphogenesis; neural crest cell fate specification; and skeletal system morphogenesis. Localizes to nuclear chromatin. Human ortholog(s) of this gene implicated in acute myeloid leukemia and autosomal dominant non-syndromic intellectual disability 32. Is expressed in head. Orthologous to human KAT6A (lysine acetyltransferase 6A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kat6a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Arboleda-Tham syndrome Alliance Arboleda-Tham syndrome 616268
Associated With kat6a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001965 Zinc finger, PHD-type
Domain IPR002717 Histone acetyltransferase domain, MYST-type
Domain IPR005818 Linker histone H1/H5, domain H15
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR040706 MYST, zinc finger domain
Family IPR031280 Histone acetyltransferase KAT6A
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR016181 Acyl-CoA N-acyltransferase
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA N-acyltransferase Histone acetyltransferase domain, MYST-type Histone acetyltransferase KAT6A Linker histone H1/H5, domain H15 MYST, zinc finger domain Winged helix-like DNA-binding domain superfamily Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q6J514 2246
UniProtKB:B3DK07 2247
UniProtKB:A2CG09 2246
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations