Gene

mt-nd6

ID
ZDB-GENE-011205-13
Name
NADH dehydrogenase 6, mitochondrial
Symbol
mt-nd6 Nomenclature History
Previous Names
  • mtnd6 (1)
  • ND6 (1)
Type
protein_coding_gene
Location
Chr: MT Mapping Details/Browsers
Description
Predicted to have NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to integral component of membrane; mitochondrial membrane; and respirasome. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and spinal muscular atrophy with lower extremity predominante 2B. Orthologous to human MT-ND6 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mt-nd6 Human Ortholog
No data available
Associated With mt-nd6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6
Family IPR050269 Complex I Subunit 6
Domain Details Per Protein
Protein Length Complex I Subunit 6 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6
UniProtKB:A0A0A0VG13 172
UniProtKB:Q9MIX9 172
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations