Gene
mt-nd4
- ID
- ZDB-GENE-011205-10
- Name
- NADH dehydrogenase 4, mitochondrial
- Symbol
- mt-nd4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: MT Mapping Details/Browsers
- Description
- Predicted to enable NADH dehydrogenase (ubiquinone) activity and ubiquinone binding activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within ATP synthesis coupled electron transport. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Parkinson's disease; macular degeneration; and schizophrenia. Orthologous to human MT-ND4 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NADH-quinone oxidoreductase, chain M/4 | NADH:ubiquinone oxidoreductase | NADH:ubiquinone oxidoreductase chain 4, N-terminal |
|---|---|---|---|---|
|
UniProtKB:Q9MIY1
|
460 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available