Gene

vcana

ID
ZDB-GENE-011023-1
Name
versican a
Symbol
vcana Nomenclature History
Previous Names
  • br146 (1)
  • cspg2
  • cspg2a (1)
  • sb:cb63
  • versican (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and hyaluronic acid binding activity. Involved in endocardial cushion morphogenesis; pronephric glomerulus morphogenesis; and regulation of glomerular filtration. Predicted to localize to extracellular matrix. Is expressed in several structures, including anterior neural keel; mesoderm; otic vesicle; pericardial region; and semicircular canal. Human ortholog(s) of this gene implicated in intracranial aneurysm. Orthologous to human VCAN (versican).
Genome Resources
Note
None
Expression
All Expression Data
56 figures from 41 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vcana Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Wagner syndrome 1 143200
Associated With vcana Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR013032 EGF-like, conserved site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Conserved_site IPR018378 C-type lectin, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000538 Link domain
Domain IPR000742 EGF-like domain
Domain IPR001304 C-type lectin-like
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
Homologous_superfamily IPR016187 C-type lectin fold
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length C-type lectin, conserved site C-type lectin fold C-type lectin-like C-type lectin-like/link domain superfamily EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like, conserved site EGF-like domain EGF-type aspartate/asparagine hydroxylation site Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin V-set domain Link domain Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily
UniProtKB:A0A2R8Q3K1 635
UniProtKB:Q1LXE5 157
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations