Gene
lcat
- ID
- ZDB-GENE-010716-3
- Name
- lecithin-cholesterol acyltransferase
- Symbol
- lcat Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have O-acyltransferase activity. Predicted to be involved in lipid metabolic process. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Is expressed in liver. Orthologous to human LCAT (lecithin-cholesterol acyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Norum disease | Alliance | Norum disease | 245900 |
| Fish-eye disease | 136120 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase |
|---|---|---|---|
|
UniProtKB:A0A8M1P7R5
|
436 |
Interactions and Pathways
No data available
Plasmids
No data available