Gene
clic3
- ID
- ZDB-GENE-010507-2
- Name
- chloride intracellular channel 3
- Symbol
- clic3 Nomenclature History
- Previous Names
-
- clica
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable lysophospholipase activity. Predicted to act upstream of or within chloride transport; glutathione metabolic process; and lipid catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of chloride channel complex. Predicted to be active in endoplasmic reticulum. Is expressed in EVL. Orthologous to several human genes including PNPLA7 (patatin like phospholipase domain containing 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6903785 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR053823 | CLIC, N-terminal domain |
| Family | IPR002946 | Intracellular chloride channel |
| Family | IPR040079 | Glutathione transferase family |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CLIC, N-terminal domain | Glutathione S-transferase, C-terminal domain superfamily | Glutathione transferase family | Intracellular chloride channel | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6P5J7
|
239 |
Interactions and Pathways
No data available
Plasmids
No data available