Gene

kat6b

ID
ZDB-GENE-000607-52
Name
K(lysine) acetyltransferase 6B
Symbol
kat6b Nomenclature History
Previous Names
  • id:ibd5103 (1)
  • si:dkey-24f15.3 (1)
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable chromatin binding activity; histone H3 acetyltransferase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within nucleosome assembly and regulation of DNA-templated transcription. Predicted to be part of MOZ/MORF histone acetyltransferase complex. Predicted to be active in chromatin and nucleus. Is expressed in forebrain. Human ortholog(s) of this gene implicated in Ohdo syndrome, SBBYS variant; bipolar disorder; breast cancer; and leiomyoma. Orthologous to human KAT6B (lysine acetyltransferase 6B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Kudoh et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kat6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ohdo syndrome, SBBYS variant Alliance SBBYSS syndrome 603736
Genitopatellar syndrome 606170
1 - 2 of 2
Associated With kat6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001965 Zinc finger, PHD-type
Domain IPR002717 Histone acetyltransferase domain, MYST-type
Domain IPR005818 Linker histone H1/H5, domain H15
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR040706 MYST, zinc finger domain
1 - 5 of 12 Show all
Domain Details Per Protein
Protein Additional Resources Length Acyl-CoA N-acyltransferase Histone acetyltransferase domain, MYST-type Linker histone H1/H5, domain H15 MYST family histone acetyltransferases MYST, zinc finger domain SAM domain-containing protein 1-like, WH domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:A0A8M3B851 InterPro 1856
UniProtKB:A0A8M3BER5 InterPro 2044
UniProtKB:A0A8M3B5C9 InterPro 1762
UniProtKB:A0A8M3AZ79 InterPro 2043
1 - 4 of 4
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA kat6b-201 (1) Ensembl 3,114 nt
mRNA kat6b-202 (1) Ensembl 4,107 nt
mRNA kat6b-203 (1) Ensembl 1,938 nt
mRNA kat6b-204 (1) Ensembl 453 nt
mRNA kat6b-205 (1) Ensembl 978 nt
1 - 5 of 5
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
1 - 6 of 6
Show