ZFIN Fish: rgs4^kbc2/kbc2

ZFIN ID: ZDB-FISH-220715-6

ZFIN ID: ZDB-FISH-220715-6

Fish name:	rgs4^kbc2/kbc2
Genotype:	rgs4^kbc2/kbc2
Targeting Reagent:	none

HUMAN DISEASE MODELED by rgs4^kbc2/kbc2
No data available

GENE EXPRESSION
Gene expression in rgs4^kbc2/kbc2

RNA expression No data available

Protein expression

Antibody	Structure	Conditions	Figures
Ab1-h3	spinal cord cell body	standard conditions	Figure 4 from Mikdache et al., 2021
Ab1-elavl	posterior lateral line ganglion neuronal cell body spinal cord neuronal cell body	standard conditions	Figure 3 , Figure 4 from Mikdache et al., 2021
Ab12-mapk	whole organism	standard conditions	Figure 5 from Mikdache et al., 2021
Ab3-rps6	nervous system whole organism	standard conditions	Figure 7 from Mikdache et al., 2021
Ab1-rps6	nervous system whole organism	standard conditions	Figure 7 from Mikdache et al., 2021
Ab9-mapk	whole organism	standard conditions	Figure 5 from Mikdache et al., 2021
Ab1-tuba	posterior lateral line nerve axon	standard conditions	Figure 2 from Mikdache et al., 2021
Ab5-akt	nervous system whole organism	standard conditions	Figure 5 from Mikdache et al., 2021
Ab3-akt	nervous system whole organism	standard conditions	Figure 5 from Mikdache et al., 2021
znp-1	CaP motoneuron axon MiP motor neuron axon RoP motor neuron axon	standard conditions	Figure 2 from Mikdache et al., 2021

Reporter gene expression No data available

PHENOTYPE
Phenotype in rgs4^kbc2/kbc2

Phenotype	Conditions	Figures
CaP motoneuron axon decreased branchiness, abnormal	standard conditions	Figure 2 from Mikdache et al., 2021
CaP motoneuron axon decreased length, abnormal	standard conditions	Figure 2 from Mikdache et al., 2021
CaP motoneuron axon extension decreased process quality, abnormal	standard conditions	Figure 2 from Mikdache et al., 2021
ERK1 and ERK2 cascade normal occurrence, normal	standard conditions	Figure 5 from Mikdache et al., 2021
head decreased size, abnormal	standard conditions	Figure 4 from Mikdache et al., 2021
heart edematous, abnormal	standard conditions	Figure 1 from Mikdache et al., 2021
nervous system ab1-rps6 labeling decreased amount, abnormal	standard conditions	Figure 7 from Mikdache et al., 2021
nervous system ab3-akt labeling increased amount, abnormal	standard conditions	Figure 5 from Mikdache et al., 2021
nervous system protein kinase B signaling decreased occurrence, abnormal	standard conditions	Figure 5 from Mikdache et al., 2021
nervous system TOR signaling decreased occurrence, abnormal	standard conditions	Figure 7 from Mikdache et al., 2021
posterior lateral line ganglion has fewer parts of type posterior lateral line ganglion neuron, abnormal	standard conditions	Figure 3 from Mikdache et al., 2021
posterior lateral line nerve morphology, normal	standard conditions	Figure 2 from Mikdache et al., 2021
posterior lateral line nerve axon extension normal process quality, normal	standard conditions	Figure 2 from Mikdache et al., 2021
protein kinase B signaling normal occurrence, normal	standard conditions	Figure 5 from Mikdache et al., 2021
spinal cord cell population proliferation increased occurrence, abnormal	standard conditions	Figure 4 from Mikdache et al., 2021
spinal cord neuron differentiation decreased occurrence, abnormal	standard conditions	Figure 4 from Mikdache et al., 2021
thigmotaxis decreased process quality, abnormal	standard conditions	Figure 2 from Mikdache et al., 2021
whole organism ab5-akt labeling decreased amount, abnormal	standard conditions	Figure 5 from Mikdache et al., 2021
whole organism ab1-rps6 labeling decreased amount, abnormal	standard conditions	Figure 7 from Mikdache et al., 2021
whole organism protein kinase B signaling decreased occurrence, abnormal	standard conditions	Figure 5 from Mikdache et al., 2021
whole organism TOR signaling decreased occurrence, abnormal	standard conditions	Figure 7 from Mikdache et al., 2021
whole organism TOR signaling normal occurrence, normal	standard conditions	Figure 7 from Mikdache et al., 2021

CITATIONS (1)