ZFIN ID: ZDB-FISH-201111-4
Fish name: sirt1yu28/yu28(AB)
Genotype: sirt1yu28/yu28 (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by sirt1yu28/yu28(AB)
No data available
GENE EXPRESSION
Gene expression in sirt1yu28/yu28(AB)
RNA expression
Expressed Gene Structure Conditions Figures
casp3a standard conditions Fig. 3 with image from Kim et al., 2019
ifng1r standard conditions Fig. 3 with image from Kim et al., 2019
il1b standard conditions Fig. 3 with image from Kim et al., 2019
il6 standard conditions Fig. 3 with image from Kim et al., 2019
mmp2 standard conditions Fig. 3 with image from Kim et al., 2019
mmp9 standard conditions Fig. 3 with image from Kim et al., 2019
mpx standard conditions Fig. 5 with image from Kim et al., 2019
nfe2l2a standard conditions Fig. 3 with image from Kim et al., 2019
nos2a standard conditions Fig. 3 with image from Kim et al., 2019
ppargc1a standard conditions Fig. 3 with image from Kim et al., 2019
ptgs2a standard conditions Fig. 3 with image from Kim et al., 2019
rela standard conditions Fig. 5 with image from Kim et al., 2019
sirt1 standard conditions Fig. 1 with imageFig. 3 with image from Kim et al., 2019
socs1a standard conditions Fig. 3 with image from Kim et al., 2019
socs3a standard conditions Fig. 3 with image from Kim et al., 2019
sod1 standard conditions Fig. 3 with image from Kim et al., 2019
tgfb1a standard conditions Fig. 3 with image from Kim et al., 2019
tgfb2 standard conditions Fig. 3 with image from Kim et al., 2019
timp2a standard conditions Fig. 3 with image from Kim et al., 2019
tnfa standard conditions Fig. 3 with imageFig. 5 with image from Kim et al., 2019
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in sirt1yu28/yu28(AB)
Phenotype Conditions Figures
apoptotic process increased occurrence, abnormal control Fig. 2 with image from Kim et al., 2019
apoptotic process increased occurrence, exacerbated chemical treatment by environment: tert-butyl hydroperoxide Fig. 2 with image from Kim et al., 2019
apoptotic process occurrence, ameliorated chemical treatment by environment: N-acetyl-L-cysteine, chemical treatment by environment: tert-butyl hydroperoxide Fig. 2 with image from Kim et al., 2019
inflammatory response increased process quality, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
intestine atrophied, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
intestine tnfa expression increased amount, abnormal standard conditions Fig. 5 with image from Kim et al., 2019
intestine rela expression increased amount, abnormal standard conditions Fig. 5 with image from Kim et al., 2019
intestine mpx expression increased amount, abnormal standard conditions Fig. 5 with image from Kim et al., 2019
intestine inflamed, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
intestine apoptotic process increased occurrence, abnormal standard conditions Fig. 5 with image from Kim et al., 2019
intestine inflammatory response increased occurrence, abnormal standard conditions Fig. 4 with imageFig. 5 with image from Kim et al., 2019
pancreas inflamed, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
pancreas inflammatory response increased occurrence, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
reactive oxygen species biosynthetic process increased occurrence, abnormal control Fig. 2 with image from Kim et al., 2019
reactive oxygen species biosynthetic process increased occurrence, exacerbated chemical treatment by environment: tert-butyl hydroperoxide Fig. 2 with image from Kim et al., 2019
reactive oxygen species biosynthetic process occurrence, ameliorated chemical treatment by environment: N-acetyl-L-cysteine, chemical treatment by environment: tert-butyl hydroperoxide Fig. 2 with image from Kim et al., 2019
spleen inflamed, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
spleen inflammatory response increased occurrence, abnormal standard conditions Fig. 4 with image from Kim et al., 2019
whole organism sirt1 expression absent, abnormal standard conditions Fig. 1 with image from Kim et al., 2019
whole organism decreased life span, abnormal standard conditions Fig. 5 with image from Kim et al., 2019
whole organism socs3a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism il6 expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism socs1a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism nfe2l2a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism il1b expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism nos2a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism casp3a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism tnfa expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism tgfb1a expression increased amount, abnormal standard conditions Fig. 3 with image from Kim et al., 2019
whole organism viability, ameliorated chemical treatment by environment: tert-butyl hydroperoxide Fig. 2 with image from Kim et al., 2019

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