ZFIN ID: ZDB-FISH-200410-2
Fish name: col1a1adc124/+ (AB)
Genotype: col1a1adc124/+ (AB)
Targeting Reagent: none
HUMAN DISEASE MODELED by col1a1adc124/+ (AB)
Human Disease Conditions Citations
osteogenesis imperfecta standard conditions Fiedler et al., 2018
GENE EXPRESSION
Gene expression in col1a1adc124/+ (AB)
RNA expression No data available
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in col1a1adc124/+ (AB)
Phenotype Conditions Figures
bone mineralization involved in bone maturation decreased rate, abnormal standard conditions Fig. 1 from Fiedler et al., 2018
centrum dysplastic, abnormal standard conditions Fig. 4 from Fiedler et al., 2018
centrum poorly ossified, abnormal standard conditions Fig. 1 from Fiedler et al., 2018
centrum bone mineralization decreased occurrence, abnormal standard conditions Fig. 1 from Fiedler et al., 2018
centrum central region calcified, abnormal standard conditions Fig. 2Fig. 3Fig. 4 from Fiedler et al., 2018
lacunocanalicular system decreased volume, abnormal standard conditions Fig. 6 from Fiedler et al., 2018
lepidotrichium deformed, abnormal standard conditions Fig. 2 from Fiedler et al., 2018
osteoblast cuboid, abnormal standard conditions Fig. 6 from Fiedler et al., 2018
osteocyte proportionality to bone tissue, abnormal standard conditions Fig. 6 from Fiedler et al., 2018
rib deformed, abnormal standard conditions Fig. 2 from Fiedler et al., 2018
rib fragile, abnormal standard conditions Fig. 1 from Fiedler et al., 2018
rib scarred, abnormal standard conditions Fig. 1 from Fiedler et al., 2018
vertebra collapsed, abnormal standard conditions Fig. 2 from Fiedler et al., 2018
vertebra fused with vertebra, abnormal standard conditions Fig. 2 from Fiedler et al., 2018
vertebral body end plate decreased elasticity, abnormal standard conditions Fig. 5 from Fiedler et al., 2018
vertebral body end plate hardness, normal standard conditions Fig. 5 from Fiedler et al., 2018
vertebral body end plate apatite crystal configuration, abnormal standard conditions Fig. 4 from Fiedler et al., 2018
vertebral body end plate carbonate increased amount, abnormal standard conditions Fig. 3Fig. 4 from Fiedler et al., 2018
vertebral body end plate collagen network immature, abnormal standard conditions Fig. 3 from Fiedler et al., 2018
vertebral body end plate phosphate decreased amount, abnormal standard conditions Fig. 3 from Fiedler et al., 2018
vertebral column decreased length, abnormal standard conditions Fig. 2 from Fiedler et al., 2018

CITATIONS  (1)