ZFIN Fish: fgf24^uc47/uc47

ZFIN ID: ZDB-FISH-180508-1

ZFIN ID: ZDB-FISH-180508-1

Fish name:	fgf24^uc47/uc47
Genotype:	fgf24^uc47/uc47 (AB)
Targeting Reagent:	none

HUMAN DISEASE MODELED by fgf24^uc47/uc47
No data available

GENE EXPRESSION
Gene expression in fgf24^uc47/uc47

RNA expression

Expressed Gene	Structure	Conditions	Figures
amh	gonad primordium somatic cell	standard conditions	Fig. 5 from Leerberg et al., 2017
cyp19a1a	gonad primordium somatic cell	standard conditions	Fig. 5 from Leerberg et al., 2017
ddx4	germ line cell gonad primordium germ line cell immature gonad germ line cell	standard conditions	Fig. 2 , Fig. 4 , Fig. 5 , Fig. 7 , Fig. 8 from Leerberg et al., 2017
etv4	gonad primordium somatic cell	standard conditions	Fig. 4 from Leerberg et al., 2017
gata4	gonad primordium somatic cell	standard conditions	Fig. 5 from Leerberg et al., 2017
nr5a1a	gonad primordium somatic cell	standard conditions	Fig. 5 from Leerberg et al., 2017
wt1a	gonad primordium somatic cell	standard conditions	Fig. 5 from Leerberg et al., 2017

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab6-cdh2		gonad primordium somatic cell	standard conditions	Fig. 8 from Leerberg et al., 2017
Ab1-lama1		(not) gonad primordium	standard conditions	Fig. 7 from Leerberg et al., 2017
Ab2-mapk		(not) gonad primordium somatic cell	standard conditions	Fig. 4 from Leerberg et al., 2017
Ab1-tjp1		gonad primordium somatic cell	standard conditions	Fig. 8 from Leerberg et al., 2017
Ab1-ctnnb		gonad primordium somatic cell	standard conditions	Fig. 8 from Leerberg et al., 2017
Ab1-ddx4	ddx4	germ line cell gonad primordium germ line cell immature gonad germ line cell	standard conditions	Fig. 2 , Fig. 4 , Fig. 5 , Fig. 7 , Fig. 8 from Leerberg et al., 2017

Reporter gene expression No data available

PHENOTYPE
Phenotype in fgf24^uc47/uc47

Phenotype	Conditions	Figures
female organism absent, abnormal	standard conditions	Table S2, text only from Leerberg et al., 2017
gonad primordium ab1-lama1 labeling absent, abnormal	standard conditions	Fig. 7 from Leerberg et al., 2017
gonad primordium germ line cell ab1-ctnnb labeling decreased amount, abnormal	standard conditions	Fig. 8 from Leerberg et al., 2017
gonad primordium germ line cell ddx4 expression decreased amount, abnormal	standard conditions	Fig. 2 from Leerberg et al., 2017
gonad primordium somatic cell ab2-mapk labeling absent, abnormal	standard conditions	Fig. 4 from Leerberg et al., 2017
gonad primordium somatic cell etv4 expression decreased amount, abnormal	standard conditions	Fig. 4 from Leerberg et al., 2017
gonad primordium somatic cell nr5a1a expression decreased amount, abnormal	standard conditions	Fig. 5 from Leerberg et al., 2017
gonad primordium somatic cell amh expression decreased amount, abnormal	standard conditions	Fig. 5 from Leerberg et al., 2017
gonad primordium somatic cell ab1-ctnnb labeling decreased amount, abnormal	standard conditions	Fig. 8 from Leerberg et al., 2017
gonad primordium somatic cell cyp19a1a expression decreased amount, abnormal	standard conditions	Fig. 5 from Leerberg et al., 2017
gonad primordium somatic cell gata4 expression decreased amount, abnormal	standard conditions	Fig. 5 from Leerberg et al., 2017
gonad primordium somatic cell morphology, abnormal	standard conditions	Fig. 7 from Leerberg et al., 2017
immature gonad germ line cell ddx4 expression decreased amount, abnormal	standard conditions	Fig. 2 from Leerberg et al., 2017
whole organism lacks all parts of type pectoral fin, abnormal	standard conditions	text only from Leerberg et al., 2017

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