ZFIN Fish: rraga^st77/st77

ZFIN ID: ZDB-FISH-170206-3

ZFIN ID: ZDB-FISH-170206-3

Fish name:	rraga^st77/st77
Genotype:	rraga^st77/st77
Targeting Reagent:	none

HUMAN DISEASE MODELED by rraga^st77/st77
No data available

GENE EXPRESSION
Gene expression in rraga^st77/st77

RNA expression

Expressed Gene	Structure	Conditions	Figures
apoeb	brain microglial cell	standard conditions	Fig. 2 from Shen et al., 2016
asah1b	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
bloc1s6	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
ctsc	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
gabarapa	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
hexb	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
mapk1	whole organism	standard conditions	Fig. 6 from Shen et al., 2016
mfap4.1	brain microglial cell	standard conditions	Fig. 2 from Shen et al., 2016
slc7a7	brain microglial cell	standard conditions	Fig. 2 from Shen et al., 2016

Protein expression

Antibody	Structure	Conditions	Figures
Ab6-sqstm1	whole organism	standard conditions	Fig. 5 from Shen et al., 2016
Ab9-rps6	whole organism	standard conditions	Fig. 1 from Shen et al., 2016
Ab2-map1lc3b	whole organism	standard conditions	Fig. 5 from Shen et al., 2016

Reporter gene expression No data available

PHENOTYPE
Phenotype in rraga^st77/st77

Phenotype	Conditions	Figures
brain has fewer parts of type microglial cell, abnormal	standard conditions	Fig. 1 , Fig. 2 from Shen et al., 2016
microglia development decreased process quality, abnormal	standard conditions	Fig. 1 , Fig. 2 from Shen et al., 2016
microglial cell lysosomal protein catabolic process decreased occurrence, abnormal	standard conditions	Fig. 5 from Shen et al., 2016
microglial cell lysosome organization process quality, abnormal	standard conditions	Fig. 4 from Shen et al., 2016
microglial cell phagolysosome increased size, abnormal	standard conditions	Fig. 4 from Shen et al., 2016
optic tectum apoptotic cell clearance decreased occurrence, abnormal	standard conditions	Fig. 4 from Shen et al., 2016
optic tectum microglial cell has extra parts of type microglial cell phagolysosome, abnormal	standard conditions	Fig. 4 from Shen et al., 2016
optic tectum microglial cell morphology, abnormal	standard conditions	Fig. 4 from Shen et al., 2016
trunk curvature, normal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism bloc1s6 expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism Ab6-sqstm1 labeling increased amount, abnormal	standard conditions	Fig. 5 from Shen et al., 2016
whole organism mapk1 expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism ctsc expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism asah1b expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism hexb expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016
whole organism gabarapa expression increased amount, abnormal	standard conditions	Fig. 6 from Shen et al., 2016

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