ZFIN ID: ZDB-FISH-160414-1
Fish name: nkuasgfp1aTg ; km5Tg ; c264Tg
Genotype: nkuasgfp1aTg ; km5Tg ; c264Tg
Targeting Reagent: none
HUMAN DISEASE MODELED by nkuasgfp1aTg ; km5Tg ; c264Tg
Human Disease Conditions Citations
demyelinating disease chemical treatment: metronidazole Kim et al., 2015
GENE EXPRESSION
Gene expression in nkuasgfp1aTg ; km5Tg ; c264Tg
RNA expression
Expressed Gene Structure Conditions Figures
apoeb control Fig. 6 from Kim et al., 2015
chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 6 from Kim et al., 2015
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab1-tuba chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 3 from Kim et al., 2015
Ab1-tuba control Fig. 3 from Kim et al., 2015
Reporter gene expression
Expressed Gene Structure Conditions Figures
GFP control Fig. 1Fig. 2Fig. 3Fig. 5 from Kim et al., 2015
chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 1Fig. 2Fig. 3Fig. 5 from Kim et al., 2015
mCherry control Fig. 1 from Kim et al., 2015
chemical treatment: metronidazole Fig. 1 from Kim et al., 2015
PHENOTYPE
Phenotype in nkuasgfp1aTg ; km5Tg ; c264Tg
Phenotype Conditions Figures
Mauthner neuron demyelinated, abnormal chemical treatment: metronidazole Fig. 1Fig. 3 from Kim et al., 2015
Mauthner neuron myelin sheath decreased amount, abnormal chemical treatment: metronidazole Fig. 3 from Kim et al., 2015
Mauthner neuron myelin sheath structure, ameliorated chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 3 from Kim et al., 2015
posterior lateral line myelinating Schwann cell amount, ameliorated chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 2Fig. 3 from Kim et al., 2015
posterior lateral line myelinating Schwann cell decreased amount, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
posterior lateral line myelinating Schwann cell degenerate, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
posterior lateral line myelinating Schwann cell structure, ameliorated chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 2 from Kim et al., 2015
posterior lateral line nerve demyelinated, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
spinal cord demyelinated, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
spinal cord cell population proliferation increased process quality, abnormal chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 5 from Kim et al., 2015
spinal cord oligodendrocyte amount, ameliorated chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 2 from Kim et al., 2015
spinal cord oligodendrocyte decreased amount, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
spinal cord oligodendrocyte degenerate, abnormal chemical treatment: metronidazole Fig. 1Fig. 2 from Kim et al., 2015
spinal cord oligodendrocyte structure, ameliorated chemical treatment: sulfasalazine, chemical treatment: metronidazole Fig. 2 from Kim et al., 2015

CITATIONS  (1)