ZFIN Fish: la781Tg

ZFIN ID: ZDB-FISH-150901-9290

ZFIN ID: ZDB-FISH-150901-9290

Fish name:	la781Tg
Genotype:	la781Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by la781Tg
No data available

GENE EXPRESSION
Gene expression in la781Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
atoh1a	cerebellum	standard conditions	Fig. 1 from Volkmann et al., 2008
cntn2	cerebellum granule cell	standard conditions	Fig. 2 from Volkmann et al., 2008
epb41b	erythroid lineage cell	standard conditions	Fig. 4 from Bai et al., 2010
gabra6b	cerebellum granular eminence granular layer corpus cerebelli granule cell medial caudal lobe	standard conditions	Fig. 3 , Fig. S1 from Volkmann et al., 2008
gata1a	erythroid lineage cell	standard conditions	Fig. 1 from Wang et al., 2015 Fig. 3 , Fig. 4 from Bai et al., 2010
hbbe3	erythroid lineage cell	standard conditions	Fig. 4 from Bai et al., 2010
hoxa2b	hindbrain	chemical treatment: SU5402	Fig. 9 from Koster et al., 2006
	hindbrain	ablation: cerebellum, chemical treatment: SU5402	Fig. 9 from Koster et al., 2006
irf4a	(not) erythroid lineage cell	standard conditions	Fig. 1 from Wang et al., 2015
lmo2	erythroid lineage cell	standard conditions	Fig. 3 from Bai et al., 2010
myb	erythroid lineage cell	standard conditions	Fig. 3 from Bai et al., 2010
neurod1	cerebellum granule cell	standard conditions	Fig. 2 from Volkmann et al., 2008
otx2b	midbrain	chemical treatment: SU5402	Fig. 9 from Koster et al., 2006
	midbrain	ablation: cerebellum, chemical treatment: SU5402	Fig. 9 from Koster et al., 2006
pax6a	cerebellum granule cell	standard conditions	Fig. 2 from Volkmann et al., 2008
pcna	kidney	standard conditions	Fig. 2 from Leung et al., 2005
ptf1a	cerebellum	standard conditions	Fig. 1 from Volkmann et al., 2008
reln	cerebellum granule cell	standard conditions	Fig. 2 from Volkmann et al., 2008
slc17a7a	cerebellum granule cell	standard conditions	Fig. 2 from Volkmann et al., 2008
slc25a38a	nucleate erythrocyte	standard conditions	Fig. S3 from Fernández-Murray et al., 2016
slc25a38b	nucleate erythrocyte	standard conditions	Fig. S3 from Fernández-Murray et al., 2016
sox7	erythroid lineage cell	standard conditions	Fig. 2 from Chung et al., 2011
sox17	erythroid lineage cell	standard conditions	Fig. 2 from Chung et al., 2011
sox18	erythroid lineage cell	standard conditions	Fig. 2 from Chung et al., 2011
sox32	erythroid lineage cell	standard conditions	Fig. 2 from Chung et al., 2011
tal1	erythroid lineage cell	standard conditions	Fig. 3 , Fig. 4 from Bai et al., 2010
zic1	hindbrain	chemical treatment: SU5402	Fig. 9 from Koster et al., 2006
	hindbrain	ablation: cerebellum, chemical treatment: SU5402	Fig. 9 from Koster et al., 2006

Protein expression No data available

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
GFP	blood cell blood vasculature blood cell caudal artery caudal vein plexus cerebellum corpus cerebelli erythroid lineage cell granular eminence granular layer corpus cerebelli granule cell head kidney hematopoietic multipotent progenitor cell hematopoietic system hindbrain intermediate cell mass of mesoderm medial caudal lobe molecular layer corpus cerebelli neuron nucleate erythrocyte	standard conditions	18 figures from 9 publications
	kidney nucleate erythrocyte nucleate erythrocyte	chemical treatment: DAPT	Fig. 3 from Zhang et al., 2018 Fig. 2 from Lee et al., 2009

PHENOTYPE
Phenotype in la781Tg

Phenotype	Conditions	Figures
caudal artery morphology, normal	standard conditions	Fig. 2 from Imamura et al., 2008
embryo development process quality, normal	standard conditions	Fig. 2 from Long et al., 2000
erythroblast increased amount, abnormal	standard conditions	Fig. 2 from Long et al., 2000
heart dilated, abnormal	standard conditions	text only from Long et al., 2000
kidney erythroblast increased amount, abnormal	standard conditions	Fig. 2 from Long et al., 2000
nucleate erythrocyte accumulation trunk musculature, abnormal	standard conditions	Fig. 2 from Long et al., 2000
nucleate erythrocyte normal amount, normal	control	Fig. 4 from Imamura et al., 2008
telomerase activity process quality, normal	control	Fig. 4 from Imamura et al., 2008
trunk red, abnormal	standard conditions	Fig. 2 from Long et al., 2000
whole organism chromosome, telomeric region length, normal	control	Fig. 4 from Imamura et al., 2008
whole organism hemoglobin complex increased amount, abnormal	standard conditions	Fig. 2 from Long et al., 2000

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