Human Disease model utilizes vu504Tg
RNA Expression
Protein Expression
Reporter Gene Expression
- Kaneb, H.M., Folkmann, A.W., Belzil, V.V., Jao, L.E., Leblond, C.S., Girard, S.L., Daoud, H., Noreau, A., Rochefort, D., Hince, P., Szuto, A., Levert, A., Vidal, S., André-Guimont, C., Camu, W., Bouchard, J.P., Dupré, N., Rouleau, G.A., Wente, S.R., Dion, P.A. (2015) Deleterious mutations in the essential mRNA metabolism factor, hGle1, in Amyotrophic Lateral Sclerosis. Human molecular genetics. 24(5):1363-73
- Jao, L.E., Wente, S.R., and Chen, W. (2013) Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system. Proceedings of the National Academy of Sciences of the United States of America. 110(34):13904-13909
- Wei, C., Thatcher, E.J., Olena, A.F., Cha, D.J., Perdigoto, A.L., Marshall, A.F., Carter, B.D., Broadie, K., and Patton, J.G. (2013) miR-153 Regulates SNAP-25, Synaptic Transmission, and Neuronal Development. PLoS One. 8(2):e57080
- Jao, L.E., Appel, B., and Wente, S.R. (2012) A zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization. Development (Cambridge, England). 139(7):1316-1326
- Maddison, L.A., and Chen, W. (2012) Nutrient Excess Stimulates β-Cell Neogenesis in Zebrafish. Diabetes. 61(10):2517-2524
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