ZFIN ID: ZDB-FISH-150901-4827
Fish name: vangl2m209/m209
Genotype: vangl2m209/m209
Targeting Reagent: none
HUMAN DISEASE MODELED by vangl2m209/m209
No data available
GENE EXPRESSION
Gene expression in vangl2m209/m209
RNA expression
Expressed Gene Structure Conditions Figures
ctslb standard conditions Fig. S3 from Jessen et al., 2002
dld standard conditions Fig. 7 with image from Warga et al., 2007
dlx3b standard conditions Fig. S3 from Jessen et al., 2002
egr2b standard conditions Fig. 5 from Ross et al., 2005
Fig. 6 with image from Carreira-Barbosa et al., 2003
Fig. S2 from Jessen et al., 2002
emx1 standard conditions Fig. S2 from Jessen et al., 2002
eya1 standard conditions Fig. 1 with image from Aman et al., 2011
mybpc1 standard conditions Fig. 1 with image from Yin et al., 2007
myod1 standard conditions Fig. 7 with image from Warga et al., 2007
Fig. 2 with imageFig. 4 with image from Yin et al., 2007
Fig. 5 from Ross et al., 2005
Fig. 6 with image from Carreira-Barbosa et al., 2003
Fig. S2 from Jessen et al., 2002
pax2b standard conditions Fig. S2 from Jessen et al., 2002
prox1a standard conditions Fig. 1 with image from Yin et al., 2007
ptch2 standard conditions Fig. 2 with image from Yin et al., 2007
shha standard conditions Fig. S3 from Jessen et al., 2002
tpma standard conditions Fig. S1 with image from Yin et al., 2007
wt1a standard conditions Fig. 6 from Ferrante et al., 2009
zic1 standard conditions Fig. S2 from Jessen et al., 2002
Protein expression
Antibody Antigen Genes Structure Conditions Figures
Ab-3A10 standard conditions Fig. 1 with image from Sun et al., 2016
Ab2-tjp1 standard conditions Fig. 5 with image from Walsh et al., 2011
Ab1-rho standard conditions Fig. 6 with image from Song et al., 2016
Ab1-tuba standard conditions Fig. 6 with image from Song et al., 2016
Ab1-arl13b standard conditions Fig. 5 with image from Walsh et al., 2011
Reporter gene expression No data available
PHENOTYPE
Phenotype in vangl2m209/m209
Phenotype Conditions Figures
actin filament organization disrupted, abnormal standard conditions Fig. 2 with image from May-Simera et al., 2010
adaxial cell shape, abnormal standard conditions Fig. 2 with image from Yin et al., 2007
cell morphogenesis disrupted, abnormal standard conditions Fig. 2 with image from Yin et al., 2007
ceratobranchial cartilage decreased amount, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
ceratohyal cartilage deformed, abnormal standard conditions Fig. 2 with image from Sisson et al., 2015
ceratohyal cartilage displaced, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
cilium assembly disrupted, abnormal standard conditions Fig. 4 with image from May-Simera et al., 2010
commissural neuron axon guidance process quality, abnormal standard conditions Fig. 1 with image from Sun et al., 2016
convergent extension disrupted, abnormal standard conditions Fig. 1 with image from May-Simera et al., 2010
convergent extension involved in axis elongation disrupted, abnormal standard conditions Fig. 6 with image from Carreira-Barbosa et al., 2003
convergent extension involved in gastrulation process quality, abnormal control Fig. 4 from Burcklé et al., 2011
CoPA anterior/posterior axon guidance decreased process quality, abnormal standard conditions Fig. 1 with image from Sun et al., 2016
CoPA axon mislocalised posteriorly, abnormal standard conditions Fig. 1 with image from Sun et al., 2016
CoPA axon misrouted, abnormal standard conditions Fig. 1 with image from Sun et al., 2016
CoPA dorsal spinal cord interneuron anterior axon guidance decreased process quality, abnormal standard conditions Fig. 1 with image from Sun et al., 2016
CoPA dorsal/ventral axon guidance process quality, normal standard conditions Fig. 1 with image from Sun et al., 2016
cranial nerve hypoplastic, abnormal chemical treatment: ethanol Fig. 3 from Swartz et al., 2014
cranium cartilage element shortened, abnormal standard conditions Fig. 2 from Swartz et al., 2014
embryonic heart tube left/right pattern formation decreased process quality, abnormal standard conditions Fig. 3 with image from May-Simera et al., 2010
establishment of mitotic spindle orientation process quality, normal standard conditions Fig. 2 with image from Zigman et al., 2011
ethmoid cartilage decreased width, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
eye decreased distance eye, abnormal standard conditions Fig. 1 with image from May-Simera et al., 2010
eye fused with eye, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
eye fused with eye, abnormal standard conditions Fig. 1 from Jessen et al., 2002
floor plate establishment of planar polarity process quality, abnormal standard conditions Fig. 5 with image from Walsh et al., 2011
fourth ventricle duplicated, abnormal standard conditions Fig. 4 from Tawk et al., 2007
heart looping disrupted, abnormal standard conditions Fig. 3 with image from May-Simera et al., 2010
inner ear altered number of otolith, abnormal standard conditions Fig. 2 with image from May-Simera et al., 2010
Kupffer's vesicle decreased fluid flow, abnormal standard conditions Fig. 6 with image from May-Simera et al., 2010
Kupffer's vesicle decreased functionality, abnormal standard conditions Fig. 6 with image from May-Simera et al., 2010
Kupffer's vesicle ciliary basal body detached from Kupffer's vesicle apical plasma membrane, abnormal standard conditions Fig. 5 with image from May-Simera et al., 2010
Kupffer's vesicle ciliary basal body mislocalised anteriorly, abnormal standard conditions Fig. 6 with image from Juan et al., 2018
Kupffer's vesicle cilium anterior orientation, abnormal standard conditions Fig. 6 with image from Juan et al., 2018
Kupffer's vesicle epithelial cilium movement involved in determination of left/right asymmetry process quality, abnormal standard conditions Fig. 4 with image from Juan et al., 2018
Kupffer's vesicle motile cilium decreased amount, abnormal standard conditions Fig. 4 with image from May-Simera et al., 2010
Kupffer's vesicle motile cilium decreased length, abnormal standard conditions Fig. 4 with image from May-Simera et al., 2010
Kupffer's vesicle motile cilium movement quality, abnormal standard conditions Fig. 6 with image from May-Simera et al., 2010
Kupffer's vesicle nucleus increased distance Kupffer's vesicle apical plasma membrane, abnormal standard conditions Fig. 5 with image from May-Simera et al., 2010
Kupffer's vesicle development disrupted, abnormal standard conditions Fig. 4 with image from May-Simera et al., 2010
left/right pattern formation disrupted, abnormal standard conditions Fig. 3 with image from May-Simera et al., 2010
Meckel's cartilage deformed, abnormal standard conditions Fig. 2 with image from Sisson et al., 2015
Meckel's cartilage displaced, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
muscle cell migration disrupted, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
myotome decreased length, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
neural fold folding delayed, abnormal standard conditions Fig. 3 from Tawk et al., 2007
neural keel increased width, abnormal standard conditions Fig. 3 from Tawk et al., 2007
neural plate increased width, abnormal standard conditions Fig. 7 with image from Warga et al., 2007
neurocranial trabecula detached from neurocranium posterior region, abnormal chemical treatment: ethanol Fig. 2 from Swartz et al., 2014
neuroepithelial cell mitotic spindle direction, normal standard conditions Fig. 2 with image from Zigman et al., 2011
otolith amount, abnormal standard conditions Fig. 2 with image from May-Simera et al., 2010
otolith development disrupted, abnormal standard conditions Fig. 2 with image from May-Simera et al., 2010
pharyngeal arch cartilage deformed, abnormal standard conditions Fig. 2 with image from Sisson et al., 2015
pharyngeal arch cartilage chondrocyte stacked, normal standard conditions Fig. 2 with image from Sisson et al., 2015
photoreceptor cell photoreceptor cell cilium length, normal standard conditions Fig. 6 with image from Song et al., 2016
post-vent region curved ventral, abnormal standard conditions Fig. 6 with image from Carreira-Barbosa et al., 2003
post-vent region decreased length, abnormal standard conditions Fig. 6 with image from Carreira-Barbosa et al., 2003
post-vent region truncated, abnormal standard conditions Fig. 7 with image from Warga et al., 2007
pronephric glomerulus unfused from pronephric glomerulus, abnormal standard conditions Fig. 6 from Ferrante et al., 2009
retinal rod cell photoreceptor outer segment length, normal standard conditions Fig. 6 with image from Song et al., 2016
rhombomere condensed, abnormal standard conditions Fig. 6 with image from Carreira-Barbosa et al., 2003
slow muscle cell decreased length, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
slow muscle cell disorganized, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
somite condensed, abnormal standard conditions Fig. 1 with image from May-Simera et al., 2010
Fig. 7 with image from Warga et al., 2007
Fig. 6 with image from Carreira-Barbosa et al., 2003
somite decreased length, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
somite increased width, abnormal standard conditions Fig. 7 with image from Warga et al., 2007
Fig. 1 with image from Yin et al., 2007
Fig. 6 with image from Carreira-Barbosa et al., 2003
somite morphology, abnormal standard conditions Fig. 1 with imageFig. 2 with image from May-Simera et al., 2010
somite filamentous actin disorganized, abnormal standard conditions Fig. 2 with image from May-Simera et al., 2010
spinal cord duplicated, abnormal standard conditions Fig. 4 from Tawk et al., 2007
striated muscle cell development disrupted, abnormal standard conditions Fig. 1 with image from Yin et al., 2007
trunk increased curvature, abnormal standard conditions Fig. 1 from Jessen et al., 2002
whole organism curved, abnormal standard conditions Fig. 3 with image from Lopez-Schier et al., 2006
whole organism decreased length, abnormal standard conditions Fig. 3 with image from Lopez-Schier et al., 2006
whole organism anterior-posterior axis decreased length, abnormal standard conditions Fig. 1 with image from May-Simera et al., 2010
Fig. 1 from Jessen et al., 2002

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